Study on the anhydrous condensation of collagen polypeptide and tricyanogen chloride.

The molecular weight of collagen-degrading polypeptides (CDPs) extracted using the alkali method from leather scraps must be expanded to improve its utilization effect. A novel polymer (CPP) was synthesized from tricyanogen chloride (TC) and CDP by mechanical force without water. According to the solution viscosity and content of water-soluble matter, the optimal condensation conditions of the n (TC)/ n (CDP) and temperature were obtained and the properties of CPP, such as the molecular weight, thermal properties, and isoelectric point were tested and analyzed. The synthesis of CPP was simulated by the substitution of l-threonine containing hydroxyl and amino groups for the condensation reaction of CDP and TC. The result illustrated that only amino groups were involved in the substitution of chlorine accomplished by the SN2 pathway. Based on this, a probable formation mechanism of CPP was proposed. As an illustration, CPP has good utilization values in the preparation of a corrugated paper jelly instead of gelatin. The preparation of polypeptide water-based adhesive by a mechanochemical method not only has good controllability in the production process but also can save water and energy.