Characterizing mild cognitive impairment in prodromal Parkinson's disease: A community-based study in China.
Chenxi PanYuqian LiJingru RenLanting LiPeiyu HuangPing-Yi XuLi ZhangWenbing ZhangMin-Ming ZhangJiu ChenWeiguo LiuPublished in: CNS neuroscience & therapeutics (2021)
MCI, specifically impairment in memory, attention/working memory, and executive domain, is present at the prodromal stage of PD. In addition, cognitive performance is correlated with motor symptoms in pPD. Our results reflect that cognitive profile, combined with motor symptoms, can help clinicians to identify individuals with pPD early, as those would be the optimal candidates for neuroprotective therapy.
Keyphrases
- working memory
- mild cognitive impairment
- cognitive decline
- parkinson disease
- transcranial direct current stimulation
- attention deficit hyperactivity disorder
- healthcare
- sleep quality
- mental health
- palliative care
- cerebral ischemia
- stem cells
- depressive symptoms
- mesenchymal stem cells
- brain injury
- cell therapy
- blood brain barrier