Hybrid Palliation for Hypoplastic Borderline Left Ventricle: One More Chance to Biventricular Repair.
Lilia OretoGiuseppe MandraffinoRita Emanuela CalaciuraDaniela PoliPlacido GittoMichele Benedetto SaittaErmanno BellantiScipione CarerjConcetta ZitoFiore Salvatore IorioPaolo GuccioneSalvatore AgatiPublished in: Children (Basel, Switzerland) (2023)
Treatment options for hypoplastic borderline left ventricle (LV) are critically dependent on the development of the LV itself and include different types of univentricular palliation or biventricular repair performed at birth. Since hybrid palliation allows deferring major surgery to 4-6 months, in borderline cases, the decision can be postponed until the LV has expressed its growth potential. We aimed to evaluate anatomic modifications of borderline LV after hybrid palliation. We retrospectively reviewed data from 45 consecutive patients with hypoplastic LV who underwent hybrid palliation at birth between 2011 and 2015. Sixteen patients (mean weight 3.15 Kg) exhibited borderline LV and were considered for potential LV growth. After 5 months, five patients underwent univentricular palliation (Group 1), eight biventricular repairs (Group 2) and three died before surgery. Echocardiograms of Groups 1 and 2 were reviewed, comparing LV structures at birth and after 5 months. Although, at birth, all LV measurements were far below the normal limits, after 5 months, LV mass in Group 2 was almost normal, while in Group 1, no growth was evident. However, aortic root diameter and long axis ratio were significantly higher in Group 2 already at birth. Hybrid palliation can be positively considered as a "bridge-to-decision" for borderline LV. Echocardiography plays a key role in monitoring the growth of borderline LV.
Keyphrases
- end stage renal disease
- ejection fraction
- chronic kidney disease
- newly diagnosed
- gestational age
- minimally invasive
- computed tomography
- pulmonary hypertension
- physical activity
- heart failure
- mass spectrometry
- aortic valve
- risk assessment
- high resolution
- coronary artery disease
- pulmonary arterial hypertension
- decision making
- weight loss
- optical coherence tomography
- congenital heart disease
- data analysis
- artificial intelligence