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Pioglitazone Metformin Complex Improves Polycystic Ovary Syndrome Comorbid Psychological Distress via Inhibiting NLRP3 Inflammasome Activation: A Prospective Clinical Study.

Qing-Jun GuoJing ShanYi-Feng XuYan-Yan HuCui-Lan HuoJing-Yun SongChao-Qun WangHui ZhouChao-Qin YuQin Huang
Published in: Mediators of inflammation (2020)
This study is the first to reveal that PM alleviates psychological distress via inhibiting NLRP3 inflammasome and improves several markers, including total testosterone.
Keyphrases
  • nlrp inflammasome
  • polycystic ovary syndrome
  • insulin resistance
  • signaling pathway
  • sleep quality
  • air pollution
  • heavy metals
  • genome wide
  • clinical trial
  • metabolic syndrome
  • dna methylation
  • type diabetes