Superior production of heavy pamamycin derivatives using a bkdR deletion mutant of Streptomyces albus J1074/R2.
Lars GläserMartin KuhlJulian StegmüllerChristian RückertMaksym MyronovskyiJörn KalinowskiAndriy LuzhetskyyChristoph WittmannPublished in: Microbial cell factories (2021)
Our findings open the door to provide rare heavy pamamycins at markedly increased efficiency and facilitate studies to assess their specific biological activities and explore this important polyketide further.
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