Clinicopathological characteristics of low-dose methotrexate-induced epidermal dysmaturation: A study of 22 patients.

Valentin AebischerMatthias HahnDaniela LendersGisela MetzlerMartin SchallerToni Silber Stephan Forchhammer

Published in: Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG (2024)

This study proposes clinicopathological criteria for the diagnosis of MTX-associated skin toxicity, aiming to increase awareness among clinicians and pathologists for early diagnosis. Early recognition can prevent potentially life-threatening progression.

Keyphrases

low dose
high dose
wound healing
high glucose
oxidative stress
soft tissue
drug induced
endothelial cells