A Novel DLG1 Variant in a Family with Brugada Syndrome: Clinical Characteristics and In Silico Analysis.
Maria d'ApolitoFrancesco SantoroRosa SantacroceGiorgia CordiscoIlaria RagnatelaGirolamo D'ArienzoPier Luigi PellegrinoNatale Daniele BrunettiMaurizio MargaglionePublished in: Genes (2023)
A DLG1 gene variant identified was associated with BrS. The variant could modify the formation of multichannel protein complexes, affecting ion channels to specific compartments in cardiomyocytes.