Procaine and saline have similar effects on articular cartilage and synovium in rat knee.

Aysun Ankay YilbasBasak AkcaBerkem BuyukakkusElham Bahador ZirhDilara ZeybekFiliz UzumcugilFatma Saricaoglu

Published in: BMC anesthesiology (2018)

Injection of procaine seems safe to use intra-articularly based on this in vivo study on rat knee cartilage. However, further studies investigating both the analgesic and histopathological effects of procaine on damaged articular cartilage and synovium models are needed.

Keyphrases

total knee arthroplasty
knee osteoarthritis
oxidative stress
anterior cruciate ligament
anterior cruciate ligament reconstruction
ultrasound guided
neuropathic pain