Procollagen-III peptide identifies adipose tissue-associated inflammation in type 2 diabetes with or without nonalcoholic liver disease.

Ilaria BarchettaF A CiminiR De GioannisG CiccarelliL BertocciniA LenziMarco Giorgio BaroniM G Cavallo

Published in: Diabetes/metabolism research and reviews (2018)

Elevated circulating PIIINP levels specifically identify T2DM individuals with AT expansion and systemic proinflammatory profile suggestive for AT dysfunction; our results point toward a new role of PIIINP as a marker of fibroinflammation in dysmetabolic conditions, likely related to AT expansion.

Keyphrases

adipose tissue
type diabetes
oxidative stress
glycemic control
insulin resistance
genome wide
high fat diet
cardiovascular disease
metabolic syndrome
gene expression
type iii
dna methylation
skeletal muscle
weight loss