Peripheral lymphocyte fluctuation as an indicator of severe immune-related adverse events in patients treated with immune checkpoint inhibitors.

Hisamitsu MiyaakiYasuhiko NakaoSyouhei NaritaKousuke MatsumotoMasanori FukushimaRyu SasakiTakuya HondaSatoshi MiumaHisamitsu MiyaakiKazuhiko Nakao

Published in: Cancer medicine (2023)

The percentage change in lymphocyte count was found to correlate with the incidence of severe irAEs. Close monitoring of the patient's condition is crucial when the lymphocyte count decreases during ICI treatment.

Keyphrases

peripheral blood
early onset
case report
risk factors
combination therapy
smoking cessation