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BRCA2 Promotes Spontaneous Homologous Recombination In Vivo.

Adam D BrownScott GreenmanAlison B ClaybonAlexander J R Bishop
Published in: Cancers (2021)
Therefore, our results demonstrate that BRCA2, as expected, is required for high-fidelity homologous recombination DNA repair in normal tissues, here in a tissue undergoing normal proliferation through normal development.
Keyphrases
  • dna repair
  • dna damage
  • dna damage response
  • gene expression
  • oxidative stress
  • breast cancer risk