High resolution melting curve analysis enables rapid and reliable detection of G6PD variants in heterozygous females.
Md Tarikul IslamSuprovath Kumar SarkerShezote TalukderGolam Sarower BhuyanAsifuzzaman RahatNafisa Nawal IslamHasan MahmudMohammad Amir HossainA K M MuraduzzamanJakia RahmanSyeda Kashfi QadriMohammod ShahidullahMohammad Abdul MannanSarabon TahuraManzoor HussainNarayan SahaShahida AkhterNazmun NaharFiroza BegumTahmina ShirinSharif AkhteruzzamanSyed Saleheen QadriFirdausi QadriKaiissar MannoorPublished in: BMC genetics (2018)
In addition to the G6PD enzyme assay, HRM curve analysis could be useful as a supplemental approach for detection of G6PD heterozygosity.