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High-Intensity Zones on MRI of the Cervical Spine in Patients: Epidemiology and Association With Pain and Disability.

Austin Q NguyenGarrett K HaradaKayla L LeverichKrishn KhannaPhilip K LouieBryce A BasquesYouping TaoFabio GalbuseraFrank NiemeyerHans-Joachim WilkeHoward S AnDino Samartzis
Published in: Global spine journal (2020)
This is the first study to evaluate the clinical significance of HIZs in the cervical spine, noting level-specific and clinical outcome-specific variations. Single-HIZs were associated with significantly more pain when located inside the fusion segment, while dual-HIZs showed no associations with patient-reported outcomes. The presence of single-HIZs may correlate with concurrent spinal pathologies and should be more closely evaluated.
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