Prenatal Multivitamin Use and MTHFR Genotype Are Associated with Newborn Cord Blood DNA Methylation.

Katharine K BriegerJohn F DouJason I FeinbergKatharine K BriegerLisa A CroenIrva Hertz-PicciottoCraig J NewschafferRebecca J SchmidtM Daniele Fallin

Published in: International journal of environmental research and public health (2020)

We observed that cord blood DNA methylation was associated with maternal supplement exposure preconception and maternal genotype. Genetic context should be considered when assessing DNA methylation effects of modifiable risk factors around the time of pregnancy.

Keyphrases

cord blood
dna methylation
genome wide
pregnancy outcomes
risk factors
gene expression
birth weight
copy number
pregnant women
body mass index
weight loss
physical activity