CircDOCK7 facilitates the proliferation and adipogenic differentiation of chicken abdominal preadipocytes through the gga-miR-301b-3p/ACSL1 axis.

Weihua TianYe LiuWenhui ZhangRuixue NieYao LingBo ZhangHao ZhangChangxin Wu

Published in: Journal of animal science and biotechnology (2023)

CircDOCK7 serves as a miRNA sponge that directly sequesters gga-miR-301b-3p away from the ACSL1 gene, thus augmenting adipogenesis in chickens. These findings may elucidate a new regulatory mechanism underlying abdominal fat deposition in chickens.

Keyphrases

metabolic syndrome
heat stress
adipose tissue
disease virus
signaling pathway
transcription factor
copy number
genome wide identification
gene expression