Salivary cytokines as biomarkers of oral cancer: a systematic review and meta-analysis.

Mayara Martina Abatti ChiamuleraCaroline Biazzolo ZancanAline Pertile RemorMarcos Freitas CordeiroFrederico Omar Gleber-NettoAntuani Rafael Baptistella

Published in: BMC cancer (2021)

Our analyses showed that the salivary levels of some cytokines are consistently different among OC, OPMD and healthy patients, indicating that these SC may represent potential diagnostic biomarkers for OC and OPMD. Despite of that, SC levels were highly variable among studies, suggesting that further technical improvement and standardization for SC measurement by ELISA is needed in order to successfully translate these biomarkers to the clinical practice.

Keyphrases

clinical practice
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
risk assessment