Impact of a restrictive antibiotic policy on the acquisition of extended-spectrum beta-lactamase-producing Enterobacteriaceae in an endemic region: a before-and-after, propensity-matched cohort study in a Caribbean intensive care unit.

Christophe Le TerrierMarco VinettiPaul BonjeanRégine RichardBruno JarrigeBertrand PonsBenjamin MadeuxPascale PiednoirFanny ArdissonElain ElieFrédéric MartinoMarc ValetteEdouard OllierSébastien BreurecMichel CarlesGuillaume Thiéry

Published in: Critical care (London, England) (2021)

Implementation of a program including a restrictive antibiotic strategy is feasible and is associated with less ESBL-E acquisition in the ICU without any worsening of patient outcome.

Keyphrases

intensive care unit
healthcare
quality improvement
klebsiella pneumoniae
mechanical ventilation
escherichia coli
public health
primary care
multidrug resistant
pseudomonas aeruginosa
mental health