Enhanced Bilosomal Properties Resulted in Optimum Pharmacological Effects by Increased Acidification Pathways.
Armin MooranianThomas FosterCorina Mihaela IonescuDaniel WalkerMelissa A JonesSusbin Raj WagleBožica KovacevicJacqueline ChesterEdan JohnstonElaine WongMarcus D AtlasMomir MikovHani Al-SalamiPublished in: Pharmaceutics (2021)
Capsules' morphology and topographic characteristics remained similar, regardless of CDCA or nano gel concentrations. The best pharmacological, anti-inflammatory, and cellular respiration, metabolism, and energy production effects were observed at high CDCA and nano gel concentrations, suggesting dose-dependent cellular protective and positive effects of CDCA when incorporated with high loading nano gel.