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Fetal cardiac abnormalities: Genetic etiologies to be considered.

Florencia PetracchiSilvina SisternaLaura IgarzabalLouise E Wilkins-Haug
Published in: Prenatal diagnosis (2019)
Congenital heart diseases are a common prenatal finding. The prenatal identification of an associated genetic syndrome or a major extracardiac anomaly helps to understand the etiopathogenic diagnosis. Besides, it also assesses the prognosis, management, and familial recurrence risk while strongly influences parental decision to choose termination of pregnancy or postnatal care. This review article describes the most common genetic diagnoses associated with a prenatal finding of a congenital heart disease and a suggested diagnostic process.
Keyphrases
  • congenital heart disease
  • pregnant women
  • genome wide
  • copy number
  • healthcare
  • palliative care
  • preterm infants
  • early onset
  • dna methylation
  • preterm birth
  • gene expression
  • pain management
  • affordable care act