Heightened Procoagulation after Post-Operative Thromboprophylaxis Completion in Patients with Metastatic Bone Disease from Primary Colorectal Cancer.
Lisa YamauraDaniel YoungLeslie SkeithMichael J MonumentCraig N JenneAntoine DufourPrism SchneiderEjaife Ono AgbaniPublished in: Journal of clinical medicine (2022)
Our data elucidates the cell biology of a prothrombo-inflammatory state caused by disease and vascular injury, and recalcitrant to thromboprophylaxis. New mechanistic insights into hypercoagulability in CRC/MBD patients may identify novel drug targets for effective thromboprophylaxis type and duration after orthopaedic surgery.
Keyphrases
- venous thromboembolism
- end stage renal disease
- direct oral anticoagulants
- ejection fraction
- newly diagnosed
- chronic kidney disease
- minimally invasive
- peritoneal dialysis
- single cell
- oxidative stress
- coronary artery bypass
- stem cells
- cell therapy
- electronic health record
- emergency department
- bone mineral density
- atrial fibrillation
- body composition
- soft tissue
- deep learning
- surgical site infection
- artificial intelligence
- adverse drug