Characterization and proteomic analysis of plasma-derived small extracellular vesicles in locally advanced rectal cancer patients.

Haiyan ChenYimin FangSiqi DaiKai JiangLi ShenJian ZhaoKanghua HuangXiaofeng ZhouKefeng Ding

Published in: Cellular oncology (Dordrecht, Netherlands) (2024)

Differential expression of sEV proteins distinguishes between GR and PR patients and holds promise as predictive markers for nCRT response and prognosis in patients with LARC. Furthermore, our findings highlight substantial alterations in sEV protein composition following nCRT.

Keyphrases

rectal cancer
end stage renal disease
locally advanced
newly diagnosed
prognostic factors
squamous cell carcinoma
peritoneal dialysis
radiation therapy
clinical trial
small molecule
patient reported outcomes
lymph node
binding protein
study protocol