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Maternal vitamin D deficiency affects the morphology and function of glycolytic muscle in adult offspring rats.

Natany G ReisAna Paula AssisNatalia LautherbachDawit Albieiro Pinheiro GonçalvesWilian A SilveiraHenrique Jorge Novaes MorganRafael R ValentimLucas Ferreira de AlmeidaLilian C HeckNeusa M ZanonTatiana E KoikeAudrei R SantosElen H MiyabaraIsis do Carmo KettelhutLuiz Carlos Carvalho Navegantes
Published in: Journal of cachexia, sarcopenia and muscle (2022)
These data show that maternal VDD selectively affects the development of type-II muscle fibres in male offspring rats but not in female offspring rats and suggest that the enhancement of their size and fatigue resistance in fast-twitch skeletal muscle (EDL) is probably due to a compensatory increase in the muscle content of Vit. D in the adult age.
Keyphrases
  • skeletal muscle
  • high fat diet
  • insulin resistance
  • birth weight
  • pregnancy outcomes
  • type diabetes
  • adipose tissue
  • electronic health record
  • pregnant women
  • big data
  • weight gain
  • childhood cancer