Association and Interaction of Genetics and Area-Level Socioeconomic Factors on the Prevalence of Type 2 Diabetes and Obesity.

Sara Jane CromerChirag M LakhaniJosep M MercaderTimothy D MajarianPhilip SchroederJoanne B ColeJose C FlorezChirag J PatelAlisa K ManningSherri-Ann M Burnett-BowieJordi MerinoMiriam S Udler

Published in: Diabetes care (2023)

Genetic and socioeconomic factors significantly interact to increase risk of T2D and obesity. Favorable area-level socioeconomic status was associated with an almost 50% lower T2D prevalence in those with high genetic risk.

Keyphrases

type diabetes
insulin resistance
metabolic syndrome
weight loss
risk factors
high fat diet induced
genome wide
weight gain
glycemic control
copy number
cardiovascular disease
dna methylation
body mass index