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JAK2, CALR, and MPL Mutation Profiles in Colombian patients with BCR-ABL Negative Myeloproliferative Neoplasms.

Ana Isabel Giraldo-RincónSara Naranjo MolinaNatalia Gomez-LoperaDaniel Camilo Aguirre-AcevedoAndrea Ucroz BenavidezKenny Mauricio Galvez-CárdenasFrancisco Cuellar AmbrosíJosé Domingo TorresSigifredo Ospina OspinaKatherine PalacioLina Maria Gaviria JaramilloCarlos Mario MuñetonGonzalo Vasquez Palacio
Published in: Colombia medica (Cali, Colombia) (2023)
Thus, this study demonstrates the importance of the molecular characterization of the JAK2, CALR and MPL mutations in Colombian patients (the genetic context of which remains unclear in the abovementioned neoplasms) to achieve an accurate diagnosis, a good prognosis, adequate management, and patient survival.
Keyphrases
  • end stage renal disease
  • tyrosine kinase
  • ejection fraction
  • newly diagnosed
  • acute lymphoblastic leukemia
  • prognostic factors
  • case report
  • chronic myeloid leukemia
  • genome wide
  • mass spectrometry