Vitellaria paradoxa Nut Triterpene-Rich Extract Ameliorates Symptoms of Inflammation on Post-Traumatic Osteoarthritis in Obese Rats.

Sabri SudirmanChun-Kai ChenBing-Ting LongHeng-Wei ChangDavid TsouZwe-Ling Kong

Published in: Journal of pain research (2020)

The Vitellaria paradoxa nut triterpene-rich extract suppressed proinflammatory mediators and attenuated the cartilage degradation and pain in osteoarthritis with an obesity rat model. As such, Vitellaria paradoxa nut triterpene-rich extract can be used as an alternative for osteoarthritis treatment.

Keyphrases

oxidative stress
rheumatoid arthritis
knee osteoarthritis
metabolic syndrome
weight loss
type diabetes
anti inflammatory
chronic pain
insulin resistance
adipose tissue
pain management
mouse model
neuropathic pain
bariatric surgery
depressive symptoms
extracellular matrix
high fat diet induced
skeletal muscle