Pharmacokinetics of YK-1169 in Healthy Subjects and pharmacokinetic/pharmacodynamic analysis by Monte Carlo Simulation.

You LiBingqian YanSiwei GuoMiaomei TianYuan LiHuan TongYunsong YuJing ShaoYuxia XinHui ChenBing XuXin Li

Published in: British journal of clinical pharmacology (2023)

YK-1169 had good antibacterial activity against CRKP and could be an option for CRKP infections. The regimen of 2.5g q8h ivgtt 2h should be considered in future clinical trials.

Keyphrases

monte carlo
clinical trial
current status
phase ii
open label
study protocol