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Genetic colocalization atlas points to common regulatory sites and genes for hematopoietic traits and hematopoietic contributions to disease phenotypes.

Christopher S ThomBenjamin F Voight
Published in: BMC medical genomics (2020)
Our findings provide a road map for gene validation experiments and novel therapeutics related to hematopoietic development, and offer a rationale for pleiotropic interactions between hematopoietic loci and disease end-points.
Keyphrases
  • genome wide
  • bone marrow
  • dna methylation
  • copy number
  • clinical trial
  • transcription factor
  • genome wide identification