A longitudinal study of convalescent plasma (CCP) donors and correlation of ABO group, initial neutralizing antibodies (nAb), and body mass index (BMI) with nAb and anti-nucleocapsid (NP) SARS-CoV-2 antibody kinetics: Proposals for better quality of CCP collections.
Silvano WendelRita Fontão-WendelRoberta FachiniGabriela CandelariaPatricia ScuracchioRuth AchkarMayra BritoLuiz Fernando ReisAnamaria CamargoMariane AmanoRafael Rahal Guaragna MachadoDanielle Bastos AraujoCamila SoaresEdison DurigonPublished in: Transfusion (2021)
Selection of CCP donors for multiple collections based on initial high nAb titers (≥1280) or BMI ≥ 30 kg/m2 provides a simple strategy to achieve higher quality in CCP programs. High IgG anti-NP levels can also be used as surrogate markers for high nAb screening.