Associations between blood concentrations of sex hormones and physical function in community-dwelling older women: a prospective cohort study.

Yuanyuan WangRakibul M IslamSultana Monira Hussain John J McNeill Susan R Davis

Published in: The journals of gerontology. Series A, Biological sciences and medical sciences (2023)

Low endogenous concentrations of testosterone and dehydroepiandrosterone were associated the greatest likelihood of physical function decline in community-based women aged >70 years. Further studies are warranted to determine whether testosterone and dehydroepiandrosterone therapy prevents functional decline in this at-risk group using sensitive measures of muscle strength and performance.

Keyphrases

community dwelling
replacement therapy
polycystic ovary syndrome
pregnancy outcomes
smoking cessation
case control
type diabetes
metabolic syndrome
mouse model
adipose tissue
insulin resistance
mesenchymal stem cells