Multiple GYPB gene deletions associated with the U- phenotype in those of African ancestry.
William J LaneNicholas S GleadallJudith AeschlimannSunitha VegeAlba Sanchis-JuanJonathan StephensJensyn Cone SullivanHelen H MahMaria AguadRobin Smeland-WagmanMatthew S LeboPrathik K Vijay KumarRichard Max KaufmanRobert C GreenWillem H OuwehandConnie M WesthoffPublished in: Transfusion (2020)
The U- phenotype in those of African ancestry is primarily associated with two different complete deletions of GYPB (with intact GYPE). Seven additional less common GYPB deletion backgrounds were found. GYPB*01N, long assumed to be the allele commonly encoding U- phenotypes, appears to be rare.