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Body mass index change and estimated glomerular filtration rate decline in a middle-aged population: health check-based cohort in Japan.

Shingo FukumaTatsuyoshi IkenoueJennifer L Bragg-GreshamEdward NortonYukari YamadaDaichi KohmotoRajiv Saran
Published in: BMJ open (2020)
In the middle-aged Japanese population, both, increase and decrease in BMI were associated with subsequent eGFR decline. Changes in risk factors mediated a small proportion of the association between BMI increase and eGFR decline. Our findings support the clinical significance of monitoring BMI as a renal risk factor.
Keyphrases
  • body mass index
  • middle aged
  • risk factors
  • small cell lung cancer
  • weight gain
  • epidermal growth factor receptor
  • tyrosine kinase
  • physical activity