Short subcutaneous infusions for symptom control in palliative medicine.
Paul HowardSandra ClawsonJohn CurtinPublished in: BMJ supportive & palliative care (2023)
SSCIs appear to be a promising additional option for administering medicines that are too irritant or large in volume for SC bolus injection. For medications with longer half-lives (eg, phenobarbital, valproate, levetiracetam), SSCI loading doses would be expected to achieve steady state and, thus, symptom relief, sooner than CSCIs alone.