Positive natural selection of N6-methyladenosine on the RNAs of processed pseudogenes.

Liqiang TanWeisheng ChengFang LiuDan Ohtan WangLinwei WuNan CaoJinkai Wang

Published in: Genome biology (2021)

Our discovery reveals a novel evolutionary role of m6A RNA modification in cleaning up the unnecessary processed pseudogene transcripts to attenuate their interference with the regulatory network of protein-coding genes.

Keyphrases

genome wide
small molecule
protein protein
transcription factor
high throughput
dna methylation
amino acid
genome wide identification
bioinformatics analysis
binding protein
nucleic acid