Methotrexate accumulation in target intestinal mucosa and white blood cells differs from non-target red blood cells of patients with Crohn's disease.

Maartje M van de MeebergJanani SundaresanMarry LinGerrit JansenEduard A StruysHerma H FidderBas OldenburgWout G N MaresNofel MahmmodDirk P van AsseldonkSvend T RietdijkLoes H C NissenNanne K H de BoerGerd BoumaMaja Bulatović ĆalasanRobert de Jongenull null

Published in: Basic & clinical pharmacology & toxicology (2024)

MTX-PG patterns differ between mucosa, PBMCs and RBCs of patients with CD.

Keyphrases

red blood cell
induced apoptosis
cell cycle arrest
high dose
endoplasmic reticulum stress
cell death
oxidative stress
low dose
signaling pathway
nk cells