Assessment of an APOBEC3B truncating mutation, c.783delG, in patients with breast cancer.
Hoda RadmaneshTessa SpethmannJulia EnßenPeter SchürmannSabin BhujuRobert GeffersNatalia AntonenkovaElza KhusnutdinovaAriane Sadr-NabaviFatemeh Homaei ShandizTjoung-Won Park-SimonPeter HillemannsHans ChristiansenNatalia BogdanovaThilo DörkPublished in: Breast cancer research and treatment (2017)
APOBEC3B*c.783delG showed evidence of modest association with breast cancer and seemed to contribute to earlier onset of the disease. These results may need to be reconciled with proposals to consider APOBEC3B as a possible therapeutic target in breast cancer.
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