Polydatin accelerates osteoporotic bone repair by inducing the osteogenesis-angiogenesis coupling of bone marrow mesenchymal stem cells via the PI3K/AKT/GSK-3β/β-catenin pathway.

Chunhao ZhouGuanyu HuYi-Kai Li Sheng Zheng

Published in: International journal of surgery (London, England) (2024)

The data above indicated that POL could accelerate osteoporotic bone repair by inducing the osteogenesis-angiogenesis coupling of BMSCs via the PI3K/AKT/GSK-3β/β-catenin pathway, which provided new insight and strategy for osteoporotic bone repair.

Keyphrases

bone mineral density
postmenopausal women
bone regeneration
body composition
endothelial cells
signaling pathway
soft tissue
vascular endothelial growth factor
bone loss
room temperature
wound healing
machine learning
deep learning