Left Ventricular Myocardial Noncompaction with Advanced Atrioventricular Conduction Disorder and Ventricular Arrhythmias in a Young Patient: Role of MIB1 Gene.
Cristina BallaMartina De RaffeleMaria Angela DeserioMariabeatrice SanchiniMarianna FarnèCecilia TrabanelliLuca RagniMauro BiffiAlessandra FerliniClaudio RapezziFrancesca GualandiMatteo BertiniPublished in: Journal of cardiovascular development and disease (2021)
Left ventricular noncompaction (LVNC) is a structural abnormality of the left ventricle, usually described as an isolated condition, or sometimes associated with other structural cardiac diseases. LVNC is generally asymptomatic, although it may present conduction disorders, arrhythmias, and heart failure. Here, we present the case of a patient who came to our attention with a severe LVNC phenotype associated with advanced AV conduction disorder, and supraventricular and ventricular arrhythmias at young age, in which a novel MIB1, likely pathogenic, variation has been identified.
Keyphrases
- left ventricular
- heart failure
- mitral valve
- cardiac resynchronization therapy
- congenital heart disease
- hypertrophic cardiomyopathy
- acute myocardial infarction
- left atrial
- aortic stenosis
- case report
- catheter ablation
- middle aged
- atrial fibrillation
- working memory
- copy number
- early onset
- pulmonary hypertension
- pulmonary artery
- acute heart failure
- acute coronary syndrome
- pulmonary arterial hypertension