Head-to-head comparison of the accuracy of saliva and nasal rapid antigen SARS-CoV-2 self-testing: cross-sectional study.
Ewoud SchuitRoderick P VenekampIrene K VeldhuijzenWouter van den BijllaardtSuzan D PasJoep J J M StohrEsther B LodderMarloes HellwichRichard MolenkampZsofia IgloiConstantijn WijersIrene H VroomCarla R S Nagel-ImmingWanda G H HanJan A J W KluytmansSusan van den HofJanneke H H M van de WijgertKarel G M MoonsPublished in: BMC medicine (2022)
The Hangzhou AllTest Biotech saliva self Ag-RDT is not reliable for SARS-CoV-2 detection, overall, and in all studied subgroups. The SD Biosensor nasal self Ag-RDT had high sensitivity in individuals with symptoms and in those without prior SARS-CoV-2 infection but low sensitivity in asymptomatic individuals and those with a prior SARS-CoV-2 infection which warrants further investigation.