Dissection of the NKG2C NK cell response against Puumala Orthohantavirus.
Hannes VietzenSvenja HartenbergerStephan W AberleElisabeth Puchhammer-StöcklPublished in: PLoS neglected tropical diseases (2021)
Our results corroborate the substantial impact of the NKG2C/HLA-E axis on PUUV-specific NK cell responses. A weak NKG2C+ NK cell response, as reflected by NKG2Cwt/del variant, may be associated with a higher risk for a severe hantavirus infections.
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