Dentofacial manifestations of fetal warfarin syndrome in a paediatric patient.
Gangadharao Morankar RahulNikhil ShrivastavaNitesh TewariVijay MathurPublished in: BMJ case reports (2022)
Anticoagulant therapy is commonly indicated during pregnancy to prevent thrombosis and prevention of prosthetic heart valve-associated thromboembolic events. Warfarin is a synthetic anticoagulant with low molecular weight and can cross the placenta resulting in congenital abnormalities termed fetal warfarin syndrome. This paper highlights the case of an 8-year-old boy with warfarin embryopathy. It highlights the extraoral and intraoral findings of the case along with the cephalometric analysis and provides insight into the phenotypic variations among the different cases reported in the literature.
Keyphrases
- atrial fibrillation
- venous thromboembolism
- direct oral anticoagulants
- oral anticoagulants
- case report
- heart failure
- intensive care unit
- pulmonary embolism
- emergency department
- aortic valve
- mitral valve
- stem cells
- coronary artery disease
- aortic stenosis
- bone marrow
- mesenchymal stem cells
- left ventricular
- smoking cessation
- transcatheter aortic valve replacement
- data analysis