Warfarin use and the risk of stroke, bleeding, and mortality in older adults on dialysis with incident atrial fibrillation.
Jingwen TanSunjae BaeJodi B SegalJunya ZhuG Caleb AlexanderDorry L SegevMara Ann McAdams-DeMarcoPublished in: Nephrology (Carlton, Vic.) (2019)
Older ESRD patients with AF who were treated with warfarin had a no difference in stroke risk, lower mortality risk, but increased major bleeding risk. The bleeding risk associated with warfarin was greater among women than men. The risk/benefit ratio of warfarin may be less favourable among older women.
Keyphrases
- atrial fibrillation
- oral anticoagulants
- direct oral anticoagulants
- left atrial
- catheter ablation
- left atrial appendage
- percutaneous coronary intervention
- venous thromboembolism
- physical activity
- chronic kidney disease
- pregnant women
- middle aged
- end stage renal disease
- blood brain barrier
- acute coronary syndrome
- coronary artery disease
- adipose tissue
- breast cancer risk