Prediction models of incontinence and sexual function one year after radical prostatectomy based on data from 20 164 prostate cancer patients.
Nora Tabea SibertTobias KurthClara BreidenbachSimone WesselmannGünther FeickErnst-Günter CarlSebastian DiengMohamad Hatem AlbarghouthAtiqullah AzizStefan BaltesElisabeth BartolfJens BedkeAndreas BlanaMarko BrockStefan ConradChristopher DarrFlorian DistlerKonstantinos DrososGregor DuweAmr GaberMarkus GiessingNina Natascha HarkeAxel HeidenreichSameh HijaziAndreas HinkelBjörn Theodor KaftanShatlyk KheiderovThomas KnollGerd LümmenInga PetersBülent PolatValentin SchrodiJens-Uwe StolzenburgZoltan VargaJulius von Süßkind-SchwendiVahudin ZugorChristoph KowalskiPublished in: PloS one (2023)
The final models showed appropriate predictive properties and can be used together with the calculated risks for specific functional impairments. Main strengths are the large study sample (> 20 000) and the inclusion of an external validation. The models incorporate meaningful and clinically available predictors ensuring an easy implementation. All predictions are displayed together with risks of frequent impairments such as pad use or erectile dysfunction such that the developed online tool provides a detailed and informative overview for clinicians as well as patients.