Neutrophil Extracellular Traps Aggravate Contrast-Induced Acute Kidney Injury by Damaging Glomeruli and Peritubular Capillaries.

Heng WangTingting GaoRuijing ZhangJie HuSiqi GaoYuwen WangXiaotong QiYun ZhouGuoping ZhengHonglin Dong

Published in: Journal of inflammation research (2023)

These findings suggest that NETs are involved in the development of CI-AKI by damaging glomerular and peritubular capillary endothelial cells. This study will provide a new strategy for clinical prevention and treatment of CI-AKI.

Keyphrases

acute kidney injury
endothelial cells
high glucose
magnetic resonance
computed tomography
combination therapy
diabetic nephropathy
vascular endothelial growth factor
contrast enhanced