An aneurysmal bone cyst at T1 treated with bone grafts containing calcitonin and methylprednisolone.
Akinori OkudaHideki ShigematsuEiichiro IwataMasato TanakaYasuhiko MorimotoKeisuke MasudaChiho OhbayashiYasuhito TanakaPublished in: Journal of orthopaedic surgery (Hong Kong) (2020)
Aneurysmal bone cysts (ABCs) rarely trigger pathological fractures. Various surgical and nonsurgical treatments have been reported for this condition. Herein, we present the examination findings and treatment for a 15-year-old girl who initially presented with adolescent idiopathic scoliosis and mild back pain, but subsequently experienced severe back pain. Magnetic resonance imaging revealed an ABC at T1, with an associated pathological fracture. We successfully treated the patient using posterior fixation with instrumentation, curettage, and bone grafts combined with calcitonin and methylprednisolone (mPSL). At 3 years post-surgery, there was no ABC recurrence and only mild back pain persisted. To our knowledge, this is the first report of open surgery (curettage and fixation) with local intralesional administration of calcitonin and mPSL for an ABC-induced pathological spinal fracture. We believe that this treatment is an effective option for ABCs associated with a pathological spinal fracture.
Keyphrases
- minimally invasive
- bone mineral density
- magnetic resonance imaging
- soft tissue
- bone loss
- spinal cord
- bone regeneration
- healthcare
- high dose
- postmenopausal women
- computed tomography
- hip fracture
- low dose
- body composition
- combination therapy
- drug induced
- acute coronary syndrome
- surgical site infection
- spinal cord injury
- high glucose
- giant cell
- diffusion weighted imaging