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Diazoxide Choline Extended-Release Tablet in People with Prader-Willi Syndrome: A Double-Blind, Placebo-Controlled Trial.

Jennifer L MillerEvelien GeversNicola BridgesJack A YanovskiParisa SalehiKathryn S ObrynbaEric I FelnerLynne M BirdAshley H ShoemakerMoris AnguloMerlin G ButlerDavid StevensonJennifer AbuzzahabTimothy BarrettMelissa LahElizabeth LittlejohnVerghese MathewNeil M CowenAnish Bhatnagar
Published in: The Journal of clinical endocrinology and metabolism (2023)
DCCR did not significantly improve hyperphagia in the primary analysis but did in participants with severe baseline hyperphagia and in the Pre-COVID analysis. DCCR treatment was associated with significant improvements in body composition and clinician reported outcomes.
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