MRI Lesion State Modulates the Relationship Between Serum Neurofilament Light and Age in Multiple Sclerosis.
Mattia RossoBrian C HealyShrishti SaxenaAnu PaulKjetil BjornevikJens KuhlePascal BenkertDavid LeppertCharles GuttmannRohit BakshiHoward L WeinerTanuja ChitinisPublished in: Journal of neuroimaging : official journal of the American Society of Neuroimaging (2021)
We propose that younger patients experience a greater elevation in sNfL than older patients in response to Gad+ lesions. Our study provides potential insights into the effects of aging on neuroinflammation in MS.
Keyphrases
- multiple sclerosis
- end stage renal disease
- ejection fraction
- chronic kidney disease
- newly diagnosed
- traumatic brain injury
- mass spectrometry
- prognostic factors
- peritoneal dialysis
- lipopolysaccharide induced
- white matter
- magnetic resonance
- inflammatory response
- patient reported
- climate change
- subarachnoid hemorrhage
- diffusion weighted imaging