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Exploring the resistance mechanism of triple-negative breast cancer to paclitaxel through the scRNA-seq analysis.

Wei GaoLinlin SunJinwei GaiYinan CaoShuqun Zhang
Published in: PloS one (2024)
In this study, we identified 3 paclitaxel resistance relevant IFs and their inhibitors, which offers essential molecular basis for paclitaxel resistance and beneficial guidance for the combination of paclitaxel in clinical TNBC therapy.
Keyphrases
  • chemotherapy induced
  • single cell
  • genome wide
  • stem cells
  • bone marrow
  • mesenchymal stem cells
  • high throughput sequencing