Caloric Restriction-Induced Decreases in Dopamine Receptor Availability are Associated with Leptin Concentration.
Julia P DunnNaji N AbumradRobert M KesslerBruce W PattersonRui LiPamela Marks-ShulmanRobyn A TamboliPublished in: Obesity (Silver Spring, Md.) (2017)
In obesity, reductions in regional D2/3R availability after VLCD are suggestive of increased endogenous DA competing with the radioligand. Changes in regional D2/3R availability were associated with decreases in leptin concentrations that occurred before clinically significant weight loss.