CT perfusion core and ASPECT score prediction of outcomes in DEFUSE 3.
May A Kim-TenserMichael MlynashMaarten G LansbergMatthew TenserSebina BulicBharathi JagadeesanSoren ChristensenAlexis SimpkinsGregory W AlbersMichael P MarksJeremy J HeitPublished in: International journal of stroke : official journal of the International Stroke Society (2020)
Higher ASPECTS (8-10) correlated with functional independence at 90 days in the DEFUSE trial. ASPECTS and core infarction volume did not modify the thrombectomy treatment effect, which indicates that patients with a target mismatch profile on perfusion imaging should undergo thrombectomy regardless of ASPECTS or core infarction volume in late time windows.