Complement component 3 and its activation split-products in saliva associate with periodontitis.
Christian DamgaardLaura MassarentiAnne Katrine DanielsenJonas H GraversenPalle HolmstrupClaus H NielsenYaseelan PalarasahPublished in: Journal of periodontology (2022)
PD-B and PD-C patients show increased complement activation compared to HCs, but no difference was found between the two disease grades. PD-B, but not PD-C, is associated with increased systemic complement activation as assessed by C3c in plasma.